Discovery Projects - Grant ID: DP0774289

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0774289

Funding Status
Closed

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Funded Activity Summary

Biochemistry of tropoelastin and elastin: the molecular architecture of elastic fibre assembly. Elastin destruction drives the progression of emphysema, a major component of chronic obstructive pulmonary disease which is a major cause of death. Loss of elastin leads to profound blockage of arteries. If we are to treat these problems we need to know how to make and repair elastin. This research will enable us to discover how elastin is constructed and define its interacting partners. We will learn how to make tissue components found in parts of the body that expand and contract such as the arteries, lung and skin. We will learn about the molecular mechanisms of elastin assembly and cell interactions, which gives us the core molecular toolkit to repair elastin tissue.

Funded Activity Details

Start Date: 07-02-2007

End Date: 06-02-2010

Funding Scheme: Discovery Projects

Funding Amount: $295,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Analytical Biochemistry | Macromolecular and Materials Chemistry | Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall) | Characterisation Of Macromolecules

ANZSRC Socio-Economic Objective (SEO)

Cardiovascular system and diseases | Skin and related disorders | Biological sciences |

Other Keywords

Analytical Biochemistry | Biological sciences | Cardiovascular system and diseases | Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall) | Characterisation Of Macromolecules | Macromolecular and Materials Chemistry | Skin and related disorders

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