Discovery Projects - Grant ID: DP0774014

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0774014

Funding Status
Closed

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Funded Activity Summary

The Dynamic Control of Chromatin Structure. A human chromosome is a highly heterogeneous global structure because along its axis, it folds to different extents to form either highly compacted domains that repress the expression of genes or less condensed regions that enable genes to be turned on. Changes to the structure or stability of chromosomes, and the corresponding alterations to gene expression, have been linked to many diseases states like defects in human development and cancer. This study will uncover the underpinning mechanism of how our chromosomes are organised into distinct functional domains, which may offer the potential to develop new strategies to correct chromosomal abnormalities.

Funded Activity Details

Start Date: 01-01-2007

End Date: 31-12-2010

Funding Scheme: Discovery Projects

Funding Amount: $263,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genetic Technologies: Transformation, Site-Directed Mutagenesis, Etc. | Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Gene Expression |

ANZSRC Socio-Economic Objective (SEO)

Prevention—biologicals (e.g. vaccines) | Biological sciences | Inherited diseases (incl. gene therapy)

Other Keywords

Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Biological sciences | Gene Expression | Genetic Technologies: Transformation, Site-Directed Mutagenesis, Etc. | Inherited diseases (incl. gene therapy) | Prevention—biologicals (e.g. vaccines)

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