Discovery Projects - Grant ID: DP0773954

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0773954

Funding Status
Closed

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Funded Activity Summary

Molecular structure and function of the glycine receptor. This proposal will employ a cutting edge approach to reveal fundamental new insights into the ways that ligand-gated ion channels, and proteins in general, work. The new knowledge and technology developed here will broaden and strengthen Australia's research expertise across a number of basic scientific disciplines. The results will also have relevance to human health. Glycine receptors have an essential role in brain function and are targets for anaesthetics and drugs of abuse. GlyRs are also important in modulating pain sensation by the brain. New insights into how natural agonists and drugs affect ion channel structure and function may lead to novel therapeutic opportunities and improved drug structure predictions.

Funded Activity Details

Start Date: 01-01-2007

End Date: 31-12-2009

Funding Scheme: Discovery Projects

Funding Amount: $263,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Chemistry | Biochemistry and Cell Biology | Membrane Biology | Biophysics

ANZSRC Socio-Economic Objective (SEO)

Nervous system and disorders | Treatments (e.g. chemicals, antibiotics) |

Other Keywords

Biochemistry and Cell Biology | Biophysics | Membrane Biology | Nervous system and disorders | Structural Chemistry | Treatments (e.g. chemicals, antibiotics)

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