Discovery Projects - Grant ID: DP0773027

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0773027

Funding Status
Closed

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Funded Activity Summary

Chemical and Biochemical Characterisation of Novel Iron Chelators with Therapeutic Potential. Resistance by cancers to established chemotherapeutics is a growing problem in the community and one that demands the development of new strategies. Chelators that target the essential element iron within cancer cells represent a novel and promising approach to this problem. The Chief Investigators represent a unique combination of expertise in coordination chemistry and the biochemistry of iron chelation. They have discovered and characterised new chelators that show marked anticancer activity, and act by a new mechanism that overcomes problems of resistance. In this project they will pursue a course that will lead to a greater understanding of how these compounds work with the outcome that new effective anticancer drugs may emerge.

Funded Activity Details

Start Date: 01-12-2007

End Date: 31-03-2010

Funding Scheme: Discovery Projects

Funding Amount: $615,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Bioinorganic Chemistry | Cell Metabolism | Inorganic Chemistry | Transition Metal Chemistry

ANZSRC Socio-Economic Objective (SEO)

Treatments (e.g. chemicals, antibiotics) | Treatments (e.g. chemicals, antibiotics) |

Other Keywords

Bioinorganic Chemistry | Cell Metabolism | Inorganic Chemistry | Transition Metal Chemistry | Treatments (e.g. chemicals, antibiotics)

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