Discovery Projects - Grant ID: DP0771859

Funding Activity

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Funded Activity Summary

An epigenetic basis for foetal programming. The social and economic impact of adult-onset diseases such as diabetes, hypertension and atherosclerosis is increasing. Evidence indicates that a mother's nutrition influences the risk of her children developing some diseases later in life. This proposal aims to elucidate the mechanism underlying this phenomenon. By understanding the mechanism through which maternal nutrition affects disease risk, we may make it possible to design early diagnosis and intervention strategies. Our work may suggest intervention strategies - such as supplementation of at-risk mothers with key molecules such as methyl donors - during foetal and early postnatal life, which could be key to preventing premature morbidity and mortality.

Funded Activity Details

Start Date: 01-01-2007

End Date: 31-12-2010

Funding Scheme: Discovery Projects

Funding Amount: $261,000.00

Funder: Australian Research Council