Discovery Projects - Grant ID: DP0771706

Funding Activity

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Funded Activity Summary

The molecular basis of macropinocytosis in mammalian cells: the composition of endosome proteins and their function. Individual cells communicate with their immediate environment by the process of macropinocytosis, a process that involves the exchange of materials between the extracellular space and a specialised region of the cell termed endosomes. It is an important process in mammalian cells being essential to the correct functioning of many tissues. This project will advance understanding of macropinocytosis at a molecular level. The project is relevant to understanding the functioning of normal cells and the means by which some pathogens can enter cells and also understanding processes involved in tumour progression and metastasis.

Funded Activity Details

Start Date: 01-01-2007

End Date: 31-12-2009

Funding Scheme: Discovery Projects

Funding Amount: $263,000.00

Funder: Australian Research Council