Discovery Projects - Grant ID: DP0771309

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0771309

Funding Status
Closed

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Funded Activity Summary

A Cytosolic Complex for Targeting Mitochondrial Proteins. Mitochondria are essential for the viability of cells, and are the major source of cellular energy via oxidative phosphorylation. A loss of mitochondrial function with age contributes to the ageing process and therefore understanding the basic functions of this organelle is an important aim in biology. In mammalian cells this organelle comprises about 1500 different proteins, 99% of which need to be imported from outside the organelle. We have found that this requires a large protein complex to target the preproteins to the organelle. This research is directed to determining the component parts of this complex and the roles each component plays in the targeting process and in mitochondrial reproduction.

Funded Activity Details

Start Date: 01-01-2007

End Date: 31-12-2009

Funding Scheme: Discovery Projects

Funding Amount: $369,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Protein Targeting And Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |

Other Keywords

Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Biological sciences | Protein Targeting And Signal Transduction

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