Discovery Projects - Grant ID: DP0770301

Funding Activity

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Funded Activity Summary

Molecular analysis of glutathione transferase interactions with drugs and physiological ligands. Proteins called glutathione transferases protect us from toxic molecules that we ingest, breathe in or are by-products of normal metabolism. The same proteins also bind to many types of drugs leading them to be excreted from the body. In this project molecular structures of glutathione transferases bound to anti-cancer drugs will be determined as the basis for devising inhibitors of the protein that will make drugs much more effective.

Funded Activity Details

Start Date: 01-01-2008

End Date: 31-12-2009

Funding Scheme: Discovery Projects

Funding Amount: $263,000.00

Funder: Australian Research Council