Discovery Projects - Grant ID: DP0667314

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0667314

Funding Status
Closed

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Funded Activity Summary

Central nervous system cytokines and morphine analgesia. Morphine remains the drug of choice for the management of moderate-to-severe pain, however its clinical effectiveness is compromised by the fact that morphine's analgesic (pain reducing) efficacy becomes less effective the more it is administered.. This project will examine how analgesic tolerance develops from a completely new approach: Namely, how stimulation of the immune system within the central nervous system is a crucial factor in the development of tolerance. Modulation of analgesia by the immune system has not been systematically studied and provides a potentially fertile ground for the development of new techniques in the management of clinical pain.

Funded Activity Details

Start Date: 18-07-2006

End Date: 17-07-2009

Funding Scheme: Discovery Projects

Funding Amount: $160,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System | Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology) | Psychology | Immunology Not Elsewhere Classified

ANZSRC Socio-Economic Objective (SEO)

Immune system and allergy | Nervous system and disorders | Palliative care |

Other Keywords

Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology) | Central Nervous System | Immune system and allergy | Immunology Not Elsewhere Classified | Nervous system and disorders | Palliative care | Psychology

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