Discovery Projects - Grant ID: DP0666572

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0666572

Funding Status
Closed

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Funded Activity Summary

Identification of functionally important autophosphorylation site(s) on ataxia telangiectasia and Rad 3 - related (ATR) protein kinase. The integrity of our genetic material must be maintained so that it can be passed on from one generation to the next and also to minimize the risk of cancer and other pathologies in an individual. There are multiple proteins involved in protecting our DNA including several enzymes that detect and signal DNA damage to a series of pathways involved in halting the passage of cells through the cell cycle so that repair can occur. This project studies the mechanism of action of one of these enzymes which will be of benefit in designing new compounds to fight disease.

Funded Activity Details

Start Date: 01-01-2006

End Date: 30-09-2009

Funding Scheme: Discovery Projects

Funding Amount: $265,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Biochemistry and Cell Biology | Gene Expression | Protein Targeting And Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

Cancer and related disorders | Biological sciences | Inherited diseases (incl. gene therapy) |

Other Keywords

Biochemistry and Cell Biology | Biological sciences | Cancer and related disorders | Enzymes | Gene Expression | Inherited diseases (incl. gene therapy) | Protein Targeting And Signal Transduction

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