Discovery Projects - Grant ID: DP0666152

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0666152

Funding Status
Closed

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Funded Activity Summary

Regulation of MHC-I and ICAM-1 by flavivirus, West Nile. This project investigates the intracellular signalling pathway responsible for the expression of genes which are critical to our immune response. We have demonstrated in a mouse model that high levels of expression of two of these genes in flavivirus encephalitis are associated with a survival advantage. We would expect this project to provide basic new information about the mechanisms of expression of these genes as well as information about the interaction of this family of viruses, flavivirus with the host.

Funded Activity Details

Start Date: 26-07-2006

End Date: 25-07-2009

Funding Scheme: Discovery Projects

Funding Amount: $262,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Protein Targeting And Signal Transduction | Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall) | Virology

ANZSRC Socio-Economic Objective (SEO)

Immune system and allergy | Infectious diseases |

Other Keywords

Biochemistry and Cell Biology | Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall) | Immune system and allergy | Infectious diseases | Protein Targeting And Signal Transduction | Virology

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