Discovery Projects - Grant ID: DP0664608

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0664608

Funding Status
Closed

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Funded Activity Summary

Modelling of transdermal transport using computational molecular simulation. Through molecular simulation, we aim to model the transport of a variety of molecules through lipid bilayers typical of human skin, identifying key transport mechanisms and properties. We anticipate that this work will provide insight into existing transdermal delivery data, helping to identify relations between the physicochemical properties of a molecule and its transport properties. Ultimately, such knowledge can facilitate the development of more efficient transdermal drug delivery, which offers significant advantages over oral delivery (which leads to high waste and variability due to drug loss in the stomach and liver) and intravenous delivery (which raises compliance issues due to the adverse psychological response of patients).

Funded Activity Details

Start Date: 04-09-2006

End Date: 03-09-2009

Funding Scheme: Discovery Projects

Funding Amount: $240,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Other Physical Sciences | Thermodynamics And Statistical Physics | Biophysics

ANZSRC Socio-Economic Objective (SEO)

Clinical health not specific to particular organs, diseases and conditions | Treatments (e.g. chemicals, antibiotics) |

Other Keywords

Biophysics | Clinical health not specific to particular organs, diseases and conditions | Other Physical Sciences | Thermodynamics And Statistical Physics | Treatments (e.g. chemicals, antibiotics)

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