Discovery Projects - Grant ID: DP0558652

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0558652

Funding Status
Closed

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Funded Activity Summary

An Integrated Approach Towards Development of Highly Specific Chemotherapeutics. Many diseases are caused or can be treated by modifying the activities of particular enzymes. Molecules that affect enzymatic activities have potential as therapeutic agents. A successful approach to the discovery of new drug molecules is to design them based on very detailed knowledge of how the target enzyme works. In this project, a highly motivated team of scientists will use state of the art instruments and their combined creativity to understand the intimate details of how one large group of enzymes work. The enzymes selected are the bimetallic hydrolases, many of which are associated with disorders including osteoporosis, mental illnesses, cystic fibrosis and various types of cancer.

Funded Activity Details

Start Date: 01-01-2005

End Date: 30-06-2008

Funding Scheme: Discovery Projects

Funding Amount: $420,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Bioinorganic Chemistry | Chemical Spectroscopy | Inorganic Chemistry |

ANZSRC Socio-Economic Objective (SEO)

Skeletal system and disorders (incl. arthritis) | Biological sciences | Chemical sciences

Other Keywords

Bioinorganic Chemistry | Biological sciences | Chemical Spectroscopy | Chemical sciences | Enzymes | Inorganic Chemistry | Skeletal system and disorders (incl. arthritis)

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