Discovery Projects - Grant ID: DP0557734

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0557734

Funding Status
Closed

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Funded Activity Summary

Anticancer drug development: Enhancing the anticancer activity of mitoxantrone. Many cancer sufferers may benefit from this work if we are able to develop more active derivatives of mitoxantrone, or develop procedures to inhibit the repair of DNA lesions induced by mitoxantrone. This may result in therapies with improved response, reduced drug dosage and/or reduced side-effects. Because this work may result in one or more patents, and possibly commercialisation with Australian (and overseas) pharmaceutical companies, there are potential commercial benefits to Australia. The "discovery" aspect of this work may also identify other cellular responses to mitoxantrone (ie specific genes which are re-expressed) and this may also reveal new targets to further enhance the activity of this drug.

Funded Activity Details

Start Date: 01-01-2005

End Date: 31-12-2007

Funding Scheme: Discovery Projects

Funding Amount: $260,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Biochemistry: Nucleic Acids | Medical Biochemistry and Metabolomics | Clinical Pharmacology And Therapeutics |

ANZSRC Socio-Economic Objective (SEO)

Cancer and related disorders

Other Keywords

Cancer and related disorders | Clinical Pharmacology And Therapeutics | Medical Biochemistry and Metabolomics | Medical Biochemistry: Nucleic Acids

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