Discovery Projects - Grant ID: DP0557615

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0557615

Funding Status
Closed

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Funded Activity Summary

Autotransporter proteins of Escherichia coli. Autoransporters are a novel class of proteins associated with bacterial virulence properties such as adhesion, invasion and biofilm formation. Despite this, limited information is available on their functional role. The aim of this project is to characterize several of the autotransporter proteins from pathogenic E. coli. The likely contribution of these proteins to infection suggests that they are potential targets for strain attenuation and vaccine strain construction. Many of these proteins also mediate bacterial aggregation and are therefore targets for novel drugs that inhibit this process. The project will be carried out with a high profile partner from Denmark and will provide opportunity for travel and technology development.

Funded Activity Details

Start Date: 01-01-2005

End Date: 31-12-2007

Funding Scheme: Discovery Projects

Funding Amount: $230,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbial Genetics | Bacteriology | Microbiology | Infectious Agents

ANZSRC Socio-Economic Objective (SEO)

Infectious diseases | Biological sciences |

Other Keywords

Bacteriology | Biological sciences | Infectious Agents | Infectious diseases | Microbial Genetics | Microbiology

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