Discovery Projects - Grant ID: DP0557295

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0557295

Funding Status
Closed

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Funded Activity Summary

Nuclear Trafficking of Apolipoprotein-E. Apolipoprotein-E (apoE) regulates specific age-related neurodegenerative and cardiovascular diseases. The role of apoE in these disorders is unclear. This project will benefit our community by providing the basic cell biology knowledge required to understand disease mechanisms and ultimately provide avenues for better treatments. Aspects of the project will focus on the modification of apoE by carbohydrates and the interaction of apoE with cellular carbohydrate-containing structures. The importance of carbohydrates in the regulation of cellular and protein function is increasingly recognised and forms a foundation for the rapidly expanding discipline of glycobiology. This project will strengthen Australia's glycobiology research capacity.

Funded Activity Details

Start Date: 01-01-2005

End Date: 21-08-2008

Funding Scheme: Discovery Projects

Funding Amount: $325,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Protein Targeting And Signal Transduction | Characterisation Of Macromolecules

ANZSRC Socio-Economic Objective (SEO)

Nervous system and disorders | Health related to ageing | Cardiovascular system and diseases |

Other Keywords

Biochemistry And Cell Biology Not Elsewhere Classified | Biochemistry and Cell Biology | Cardiovascular system and diseases | Characterisation Of Macromolecules | Health related to ageing | Nervous system and disorders | Protein Targeting And Signal Transduction

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