Discovery Projects - Grant ID: DP0452833

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0452833

Funding Status
Closed

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Funded Activity Summary

Electric field induced surface attachment and detachment of proteins. Microarrays are revolutionising the diagnosis of disease by enabling large amounts of data on genetics and protein expression to be obtained from one sample. Biosensors for diseases and toxins rely on the same mechanism, namely attachment of biological macromolecules to a surface. We propose a new method for controlling the attachment by micromachining an electrode system to apply an electric field to chosen sites. Ultimately microelectronic engineering methods will be used. This will give control over the attachment process with potential benefits of orienting attaching molecules, minimising non-specific attachment and enriching diagnostics by enabling interrogation of the force of attachment.

Funded Activity Details

Start Date: 01-04-2004

End Date: 01-04-2007

Funding Scheme: Discovery Projects

Funding Amount: $505,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nanotechnology | Nanotechnology | Biomaterials | Biophysics

ANZSRC Socio-Economic Objective (SEO)

Diagnostics |

Other Keywords

Biomaterials | Biophysics | Diagnostics | Nanotechnology

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