Discovery Projects - Grant ID: DP0452629

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0452629

Funding Status
Closed

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Funded Activity Summary

Synthesis and assembly of bacterial repeat unit polysaccharides. Bacteria make an enormous range of surface polysaccharides. The complexity was first appreciated as antigenic diversity, but we now have hundreds of chemical structures and perhaps a hundred sequences of their gene clusters, but the number in nature must be many thousands. Our knowledge of gene function is growing but is not keeping up with the discovery of new sequences and structures. The aim is to determine structure and function of key O antigen processing genes and the functions of a range of glycosyl transferases, and to use the information to generate novel gene clusters to synthesise novel polysaccharides

Funded Activity Details

Start Date: 01-06-2004

End Date: 01-06-2007

Funding Scheme: Discovery Projects

Funding Amount: $225,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Agricultural Biotechnology | Molecular Evolution | Genetic Engineering And Enzyme Technology | Bacteriology

ANZSRC Socio-Economic Objective (SEO)

Infectious diseases | Biological sciences |

Other Keywords

Agricultural Biotechnology | Bacteriology | Biological sciences | Genetic Engineering And Enzyme Technology | Infectious diseases | Molecular Evolution

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