Discovery Projects - Grant ID: DP0451663

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0451663

Funding Status
Closed

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Funded Activity Summary

Molecular evolution and toxinology of colubrid snake venom toxins. This project proposes to examine the origin and evolution of venom systems in advanced snakes (Caenophidia) focusing on the colubrid radiation comprising the rear-fanged species. Demonstration by us of the presence of a potent postsynaptic neurotoxin in the Durvenoy's secretions of the Asian ratsnake Elaphe radiata, an archetypal non-venomous colubrid species, forced a fundamental rethink of venom evolution. The toxin is homologous with the three finger toxins, previously thought unique to elapids, and supports the role of venom as a key evolutionary innovation in the diversification of advanced snakes. This project extends this work to other species and toxin families.

Funded Activity Details

Start Date: 12-01-2004

End Date: 31-12-2006

Funding Scheme: Discovery Projects

Funding Amount: $225,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Molecular Evolution | Pharmacology Not Elsewhere Classified | Animal Systematics, Taxonomy And Phylogeny | Genetics

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |

Other Keywords

Animal Systematics, Taxonomy And Phylogeny | Biological sciences | Genetics | Molecular Evolution | Pharmacology Not Elsewhere Classified

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