Discovery Projects - Grant ID: DP0451178

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0451178

Funding Status
Closed

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Funded Activity Summary

Molecular genetic analysis of genes controlling morphogenesis: Dimorphic switching in the fungus Penicillium marneffei. Fungi exist in two predominant growth forms; unicellular yeast and multicellular mould (filamentous hyphae). Some fungi can alternate between these two forms in response to environmental stimuli, a process known as dimorphic switching. The cells of these two forms have distinctive shapes and physiological capacities established by genome-wide expression patterns that are triggered by signalling pathways. This research aims to understand the fundamental mechanisms controlling dimorphic switching using Penicillium marneffei, a model system. P. marneffei switches between yeast and filamentous forms in response to temperature. Uncovering the molecular mechanisms that control dimorphic switching has important implications for biotechnology and medicine.

Funded Activity Details

Start Date: 13-01-2004

End Date: 31-12-2007

Funding Scheme: Discovery Projects

Funding Amount: $255,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbial Genetics | Gene Expression | Genetics | Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

Organic industrial chemicals not classified elsewhere | Biological sciences |

Other Keywords

Biological sciences | Gene Expression | Genetic Development (Incl. Sex Determination) | Genetics | Microbial Genetics | Organic industrial chemicals not classified elsewhere

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