Discovery Projects - Grant ID: DP0449765

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0449765

Funding Status
Closed

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Funded Activity Summary

Central Muscarinic Receptors as Novel Drug Targets for Parkinson's Disease and Schizophrenia. Psychiatric and neurodegenerative disorders such as schizophrenia and Parkinson's disease are linked to alterations in the activity of neurons in the brain containing the chemical dopamine. Other types of brain neurons containing the chemical acetylcholine regulate dopamine neuron activity by acting on acetylcholine receptors located on dopamine neurons. We aim to determine how these important receptors regulate dopamine neuron activity using genetically modified mice deficient in acetylcholine receptors, together with newly developed physiological methods and new acetylcholine receptor drugs. These studies will foster the design of novel acetylcholine receptor drugs as effective pharmaceutical treatments of neurological and psychiatric disorders related to brain dopamine dysfunction.

Funded Activity Details

Start Date: 01-01-2004

End Date: 31-03-2005

Funding Scheme: Discovery Projects

Funding Amount: $140,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Animal Physiology—Systems | Central Nervous System | Biochemistry and Cell Biology | Cell Neurochemistry

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |

Other Keywords

Animal Physiology—Systems | Biochemistry and Cell Biology | Biological sciences | Cell Neurochemistry | Central Nervous System

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