Discovery Projects - Grant ID: DP0449663

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0449663

Funding Status
Closed

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Funded Activity Summary

Further Genetic and Molecular studies of an Important Prokaryotic Regulator Protein TyrR. Genomes encode many functions whose expression varies dramatically depending on particular cellular environments. Special proteins called Regulator Proteins act as sensors to detect subtle changes in the environment and, in response, to influence the expression of certain genes either dampening them down or stimulating their activity. We are working with the TyrR regulator protein of the simple bacterium Escherichia coli to elucidate the molecular strategies used in these controls. Because this protein controls the expression of a number of genes with diverse functions, evolution has selected equally diverse mechanisms to achieve appropriate transcriptional responses. The detailed knowledge of the E.coli genome and of the various genes regulated by TyrR make it an excellent system for such fundamental studies.

Funded Activity Details

Start Date: 13-01-2004

End Date: 31-12-2006

Funding Scheme: Discovery Projects

Funding Amount: $225,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbial Genetics | Molecular Evolution | Gene Expression | Genetics

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |

Other Keywords

Biological sciences | Gene Expression | Genetics | Microbial Genetics | Molecular Evolution

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