Discovery Projects - Grant ID: DP0346823

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0346823

Funding Status
Closed

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Funded Activity Summary

Linking mutant zebrafish phenotypes with their underlying genetic lesions. Zebrafish mutants have been generated with many interesting abnormalities, but to understand these abnormalities, the defective genes must be identified by positional cloning. We seek to identify the defective genes underpinning four mutants. Mutant #562 develops a normal nervous system which then undergoes rapid degeneration. The mutant flotte lotte has abnormal gut development. Two mutants with defective early blood formation will be studied. We will establish techniques for several steps that will be useful for all zebrafish mapping projects. We expect the genetic characterization of these mutants to provide new insights into nerve cell survival, gut development, and blood formation.

Funded Activity Details

Start Date: 01-01-2003

End Date: 31-12-2004

Funding Scheme: Discovery Projects

Funding Amount: $112,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genetics Not Elsewhere Classified | Genetics | Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

Inherited diseases (incl. gene therapy) |

Other Keywords

Genetic Development (Incl. Sex Determination) | Genetics | Genetics Not Elsewhere Classified | Inherited diseases (incl. gene therapy)

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