Discovery Projects - Grant ID: DP0346797

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0346797

Funding Status
Closed

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Funded Activity Summary

Organisation, expression and diversity of the sub-telomeric regions of the ancient eukaryote, Giardia duodenalis. We propose to extend our findings on the extreme plasticity of the structure and organisation of the sub-telomeric region of the complete genome of Giardia by more extensive chromosome walking, and comparison of different isolates. These regions are subject to gene conversion, transcriptional silencing, gene mobility, recombination, variable surface protein expression, subtelomeric instability and the insertion of transposable elements, a dynamic balance between structural conservation and rapid evolution. This is a rare opportunity to understand the forces at work in moulding eukaryotic sub-telomeric sequences because Giardia is not constrained by sexual homogenisation and the dynamic variability is retained.

Funded Activity Details

Start Date: 01-01-2003

End Date: 30-04-2006

Funding Scheme: Discovery Projects

Funding Amount: $255,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Molecular Evolution | Gene Expression | Genome Structure | Genetics |

ANZSRC Socio-Economic Objective (SEO)

Biological sciences | Other

Other Keywords

Biological sciences | Gene Expression | Genetics | Genome Structure | Molecular Evolution | Other

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