Discovery Projects - Grant ID: DP0346726

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0346726

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Molecular mechanisms of stem cell self-renewal. Muscle growth and regeneration is critically dependent on its stem cell compartment. We have discovered that the p38 MAPK pathway is essential for stem cell self-renewal in the C2C12 myogenic cell line. This proposal seeks to understand the molecular basis of stem cell self-renewal in skeletal muscles, data that may be applicable to many stem cell systems, and to the enormous promise of stem cell therapies for injury and diseases of the aged. We will attempt to alter the balance of stem cell production by enforced p38 expression, and take microarray and proteomics approaches to define stem cell pathways.

Funded Activity Details

Start Date: 01-01-2003

End Date: 31-12-2005

Funding Scheme: Discovery Projects

Funding Amount: $240,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Gene Expression | Protein Targeting And Signal Transduction | Cell Development (Incl. Cell Division And Apoptosis)

ANZSRC Socio-Economic Objective (SEO)

Skeletal system and disorders (incl. arthritis) | Cardiovascular system and diseases | Inherited diseases (incl. gene therapy) |

Other Keywords

Biochemistry and Cell Biology | Cardiovascular system and diseases | Cell Development (Incl. Cell Division And Apoptosis) | Gene Expression | Inherited diseases (incl. gene therapy) | Protein Targeting And Signal Transduction | Skeletal system and disorders (incl. arthritis)

Related Links