Discovery Projects - Grant ID: DP0346664

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0346664

Funding Status
Closed

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Funded Activity Summary

Regulation of mammalian differentiation by methylation of histones and transcription factors. The objective of this proposal is to examine the functional role of arginine and lysine methylation during skeletal muscle differentiation. Differentiation, i.e the acquisition of a specific phenotype, is the biological end point of the ?Genome-Phenome? transition. Specifically, the proposal will seek to understand the role of protein methylation in the control of tissue specific gene expression and cell signaling during differentiation. Key areas of study in the ARC priority area of Genome-Phenome research. We will test the hypothesis that the activity/function of the hierarchical myogenic transcription factors and cofactors that control skeletal myogenesis is influenced by protein methylation.

Funded Activity Details

Start Date: 01-01-2003

End Date: 31-12-2006

Funding Scheme: Discovery Projects

Funding Amount: $225,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry And Cell Biology Not Elsewhere Classified | Gene Expression | Genetics | Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |

Other Keywords

Biochemistry And Cell Biology Not Elsewhere Classified | Biological sciences | Gene Expression | Genetic Development (Incl. Sex Determination) | Genetics

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