Discovery Projects - Grant ID: DP0346317

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0346317

Funding Status
Closed

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Funded Activity Summary

A molecular structure-function investigation of major membrane channels involved in olfactory transduction. Olfactory receptor neurons are extraordinarily-sensitive sensors for detecting minute concentrations of odorant molecules. This project aims to extend our previous studies of these specialised mammalian olfactory cells by using state-of-the art technologies: electrophysiology (patch-clamp) and molecular biology (site-directed-mutagenesis), to investigate how the molecular structure of their ion channels (selective protein pores) and receptors contribute to the odorant-induced generation of electrical activity, which mediates our sense of smell (olfaction). The project has specific relevance for understanding olfaction, as well as relevance for other sensory systems and other ion channels.

Funded Activity Details

Start Date: 03-04-2003

End Date: 30-06-2007

Funding Scheme: Discovery Projects

Funding Amount: $225,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Sensory Systems | Physiology | Membrane Biology | Animal Physiology—Cell

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |

Other Keywords

Animal Physiology—Cell | Biological sciences | Membrane Biology | Physiology | Sensory Systems

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