Discovery Projects - Grant ID: DP0346228

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0346228

Funding Status
Closed

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Funded Activity Summary

Developmental Switches: Nuclear Transport and Spermatogenesis. We propose to test the novel hypothesis that changes in the nuclear import machinery are a key facet of cellular differentiation. We will investigate a new paradigm in developmental biology regarding whether differentiation is achieved, or can be directed, by altering transport of macromolecules, such as specific transcription factors, into the nucleus. This project will define changes in the nuclear import machinery that accompany germ and somatic cell differentiation in the developing and adult mammalian testis. This will be linked to changes in the function of key proteins acting within the nucleus using both in vitro and in vivo approaches.

Funded Activity Details

Start Date: 01-01-2003

End Date: 31-12-2007

Funding Scheme: Discovery Projects

Funding Amount: $60,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Gene Expression | Protein Targeting And Signal Transduction | Cell Development (Incl. Cell Division And Apoptosis)

ANZSRC Socio-Economic Objective (SEO)

Reproductive system and disorders | Biological sciences |

Other Keywords

Biochemistry and Cell Biology | Biological sciences | Cell Development (Incl. Cell Division And Apoptosis) | Gene Expression | Protein Targeting And Signal Transduction | Reproductive system and disorders

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