Discovery Projects - Grant ID: DP0345994

Funding Activity

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Funded Activity Summary

A genomic approach to the mechanism of meiotic recombination in Neurospora. Recombination shuffles DNA sequences between homologous chromosomes during the reduction division in the life cycle of higher organisms. Along with mutation, it is a key process in evolution. Understanding of the molecular processes involved in recombination is largely based on yeast, which is intolerant of significant levels of sequence mismatch, limiting the resolution of analyses of normal recombination events. We have shown that Neurospora, like other less tractable multicellular eukaryotes, is tolerant of sequence mismatch, allowing high resolution analysis of individual recombination events. This project will build on fundamental advances we have already made in understanding how recombination occurs.

Funded Activity Details

Start Date: 01-01-2003

End Date: 31-12-2008

Funding Scheme: Discovery Projects

Funding Amount: $500,000.00

Funder: Australian Research Council