Discovery Projects - Grant ID: DP0345915

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0345915

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Functional studies on a novel, brain-specific, Golgi ATP-binding protein in membrane trafficking. In cells specialised for communication such as neurones, protein transport constitutes a large part of total cellular activity. A primary pathway in protein transport is trafficking from the Golgi apparatus to the cell membrane; materials destined for the cell membrane and secretion are sorted, packed and transported from the Golgi apparatus. However, the mechanisms underlying these processes at the Golgi remain largely unknown. We have recently cloned a novel ATP-binding protein specifically expressed at the Golgi apparatus in human brain, and hypothesise that this protein regulates Golgi protein trafficking by interacting with two other molecules, dynamin and calcium, during cell secretion.

Funded Activity Details

Start Date: 01-01-2003

End Date: 31-12-2005

Funding Scheme: Discovery Projects

Funding Amount: $315,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Protein Targeting And Signal Transduction | Membrane Biology | Cell Neurochemistry

ANZSRC Socio-Economic Objective (SEO)

Nervous system and disorders | Endocrine organs and diseases (incl. diabetes) |

Other Keywords

Biochemistry and Cell Biology | Cell Neurochemistry | Endocrine organs and diseases (incl. diabetes) | Membrane Biology | Nervous system and disorders | Protein Targeting And Signal Transduction

Related Links