Discovery Projects - Grant ID: DP0345404

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0345404

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Bifunctional Metal Complexes as Artificial Nucleases. This study will develop new compounds with designed and molecularly engineered shapes which bind either one or two metal ions and act as artificial nucleases (i.e. catalyse the cleavage of DNA). It will produce and examine the properties and reactions of molecules which provide two linked or adjacent DNA interaction sites and which influence and direct biological activity through their shape, size and metal binding groups. Investigations will be pursued of the reactivity of copper, zinc and cobalt complexes of these molecules as artificial nucleases with model systems and for site-specific RNA and DNA cleavage of potential pharmaceutical interest.

Funded Activity Details

Start Date: 01-05-2003

End Date: 31-12-2007

Funding Scheme: Discovery Projects

Funding Amount: $162,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Bioinorganic Chemistry | Inorganic Chemistry | Transition Metal Chemistry |

ANZSRC Socio-Economic Objective (SEO)

Treatments (e.g. chemicals, antibiotics) | Chemical sciences

Other Keywords

Bioinorganic Chemistry | Chemical sciences | Inorganic Chemistry | Transition Metal Chemistry | Treatments (e.g. chemicals, antibiotics)

Related Links