Discovery Projects - Grant ID: DP0345336

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0345336

Funding Status
Closed

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Funded Activity Summary

Mechanisms of calcium handling and their role in controlling smooth muscle function: evidence from transgenic mice. Calcium movements into and out of the cytoplasm of smooth muscle cells are regulated primarily by a variety of proteins located in the plasma membrane and in the sarcoplasmic reticulum and play a central role in controlling the contractile state of smooth muscle. Understanding the mechanisms that control intracellular calcium levels is fundamental to understanding smooth muscle function. This project will employ a unique approach, involving the use of mice with targeted disruptions to genes encoding key calcium transport proteins, to gain new knowledge on the contribution of various calcium handling pathways to overall control of smooth muscle function.

Funded Activity Details

Start Date: 01-01-2003

End Date: 31-12-2005

Funding Scheme: Discovery Projects

Funding Amount: $255,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Transgenesis | Cell Physiology | Medical Physiology

ANZSRC Socio-Economic Objective (SEO)

Urogenital system and disorders | Cardiovascular system and diseases | Treatments (e.g. chemicals, antibiotics) |

Other Keywords

Cardiovascular system and diseases | Cell Physiology | Medical Physiology | Transgenesis | Treatments (e.g. chemicals, antibiotics) | Urogenital system and disorders

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