Discovery Projects - Grant ID: DP0345221

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0345221

Funding Status
Closed

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Funded Activity Summary

Subcellular co-localisation of interacting proteins that control maturation in mammalian eggs. The final maturation of mammalian eggs (oocytes) before fertilisation involves a cascade of interactions between protein kinases and phosphatases, the shuttling of these proteins between cytoplasm and nucleus, and microtubule assembly and disassembly. In this project we have proposed that interacting proteins involved in oocyte maturation are co-localised at subcellular sites in oocytes, in a strict temporal and spatial manner. The co-localisation of proteins in oocytes is considered a fundamental mechanism that ensures coordination of time-bound cellular events and proper preparation of oocytes for fertilisation and early embryo development. There are important implications for IVF and cloning by nuclear transfer.

Funded Activity Details

Start Date: 01-01-2003

End Date: 30-06-2006

Funding Scheme: Discovery Projects

Funding Amount: $83,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Animal Reproduction | Biochemistry And Cell Biology Not Elsewhere Classified | Cell Development (Incl. Cell Division And Apoptosis) | Animal Production

ANZSRC Socio-Economic Objective (SEO)

Dairy cattle | Reproductive system and disorders | Beef cattle |

Other Keywords

Animal Production | Animal Reproduction | Beef cattle | Biochemistry And Cell Biology Not Elsewhere Classified | Cell Development (Incl. Cell Division And Apoptosis) | Dairy cattle | Reproductive system and disorders

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