Discovery Projects - Grant ID: DP0344480

Funding Activity

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Funded Activity Summary

Kingdom switching microbial pathogens: the bioinformatics of mutation in the genomes of viruses and bacteria affecting crops, livestock and people. Some organisms that cause infectious diseases have moved between plants and vertebrates, either recently or repeatedly over evolutionary time. Switching between plants and vertebrates strongly influences the way these microbes mutate and evolve. We will search the genomic sequence databases for information about how the choice of host influences mutations in viral and bacterial genomes and model the evolutionary processes involved. This project will advance our understanding of the fine structure of microbial genomes and the importance of selection pressures on genes. It will lead to better disease management strategies for humans, and for domestic crops and livestock.

Funded Activity Details

Start Date: 04-06-2003

End Date: 03-06-2008

Funding Scheme: Discovery Projects

Funding Amount: $401,605.00

Funder: Australian Research Council