Discovery Projects - Grant ID: DP0344254

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0344254

Funding Status
Closed

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Funded Activity Summary

Interactions between phenome and genome at developing CNS synapses during synaptic refinement. Activity-dependent changes in synaptic transmission are vital to development and function of central neuronal networks. However, the critical factors regulating developmental changes in synaptic signals remain largely unknown. We will correlate functional changes in synaptic responses at glutamate-releasing synapses with changes in glutamate receptor composition at a critical period during development, test whether synaptic activation of receptors is required for these changes and define the pattern of activity-dependent changes in gene expression necessary for developmental changes in synaptic transmission. Understanding this interaction between synaptic phenome and activity-dependent genomic expression will expand our understanding of brain development and function.

Funded Activity Details

Start Date: 01-01-2003

End Date: 31-12-2004

Funding Scheme: Discovery Projects

Funding Amount: $125,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System | Neurosciences

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |

Other Keywords

Biological sciences | Cellular Nervous System | Neurosciences

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