Discovery Projects - Grant ID: DP0343989

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0343989

Funding Status
Closed

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Funded Activity Summary

Muscarinic Receptor Regulation of Dopamine Reward Pathways in the Brain. Human disorders such as schizophrenia and drug addiction are linked to alterations in the activity of neurons in the brain containing the chemical dopamine. Other types of brain neurons containing the chemical acetylcholine regulate the activity of dopamine neurons by acting on acetylcholine receptors located on dopamine neurons. We aim to examine how dopamine neuron activity is regulated by these receptors using newly developed physiological methods together with a new acetylcholine receptor drug. We also aim to assess the suitability of mice genetically modified to be deficient in acetylcholine receptors as animal models of dopamine dysfunction related to schizophrenia and drug addiction.

Funded Activity Details

Start Date: 27-02-2003

End Date: 31-03-2004

Funding Scheme: Discovery Projects

Funding Amount: $60,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Animal Physiology—Systems | Central Nervous System | Biochemistry and Cell Biology | Cell Neurochemistry

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |

Other Keywords

Animal Physiology—Systems | Biochemistry and Cell Biology | Biological sciences | Cell Neurochemistry | Central Nervous System

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