Discovery Projects - Grant ID: DP0343431

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0343431

Funding Status
Closed

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Funded Activity Summary

Isolation and analysis of novel caspases. Apoptosis is an evolutionarily conserved cellular process which must be tightly controlled for normal development and to avoid disease. Rapid progress has been made recently in the elucidation of apoptotic pathways, but many important components are likely still unknown. The caspases constitute the effector arm of apoptotic signalling pathways and some members play important roles in cytokine maturation. We aim to identify novel caspases using an innovative technique, and to characterise their function and regulation. Molecules identified in this project may be candidate targets for therapies which modulate apoptosis for treatment or prevention of disease, or diagnostic reagent development.

Funded Activity Details

Start Date: 07-01-2003

End Date: 31-12-2005

Funding Scheme: Discovery Projects

Funding Amount: $195,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Biochemistry and Cell Biology | Protein Targeting And Signal Transduction | Cell Development (Incl. Cell Division And Apoptosis)

ANZSRC Socio-Economic Objective (SEO)

Clinical health not specific to particular organs, diseases and conditions | Diagnostic methods |

Other Keywords

Biochemistry and Cell Biology | Cell Development (Incl. Cell Division And Apoptosis) | Clinical health not specific to particular organs, diseases and conditions | Diagnostic methods | Enzymes | Protein Targeting And Signal Transduction

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