Discovery Projects - Grant ID: DP0342987

Funding Activity

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Funded Activity Summary

Automated bioinformatic analysis of vertical and lateral gene transmission among microbial genomes. Genetic information is transmitted "vertically" from parents to offspring within species. Biologists have long assumed that this mechanism, extrapolated far into the past, explains the distribution of genes among genomes, thus the potential properties of all phenomes. But genome sequences show that some, perhaps many, genes have been transmitted "laterally" between species. We are building a unique automated computer-based system to find all instances of lateral transmission in all microbial genomes, using rigorous methods. Our results will be important both fundamentally and practically, e.g. in explaining sets and dynamics of phenomic traits, and quantifying background levels of "natural genetic engineering".

Funded Activity Details

Start Date: 01-01-2003

End Date: 31-12-2007

Funding Scheme: Discovery Projects

Funding Amount: $200,000.00

Funder: Australian Research Council