Discovery Projects - Grant ID: DP0212061

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0212061

Funding Status
Closed

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Funded Activity Summary

Identification of Proteins that Regulate Apoptosis Through Interaction With IAPS. Apoptosis is the process by which multicellular organisms eliminate unwanted cells. Identifying proteins involved in cell death regulation is central to our understanding of disease states arising from aberrations in this process. The mammalian protein DIABLO, promotes cell death by interacting with and antagonising inhibitor of apoptosis proteins (IAPS). Given the existence of several IAP regulatory proteins (IRPs) in insects, other mammalian IRPs probably also exist. These may be of equal importance in regulating apoptosis, especially in tissues where DIABLO is not expressed. The main aim of the proposed study is to idenitify and characterise other IRPs in mammalian cells.

Funded Activity Details

Start Date: 01-01-2002

End Date: 31-12-2006

Funding Scheme: Discovery Projects

Funding Amount: $465,483.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Analytical Biochemistry | Protein Targeting And Signal Transduction | Cell Development (Incl. Cell Division And Apoptosis)

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |

Other Keywords

Analytical Biochemistry | Biochemistry and Cell Biology | Biological sciences | Cell Development (Incl. Cell Division And Apoptosis) | Protein Targeting And Signal Transduction

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