Discovery Projects - Grant ID: DP0211559

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0211559

Funding Status
Closed

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Funded Activity Summary

Bacterial innovation and evolution: Molecular prospecting by targeting integrons and gene cassettes. Bacteria can respond rapidly to environmental change by acquiring new genes via lateral gene transfer. A DNA element called the integron can capture, mobilise and express genes, thereby playing a role in the transfer process. We have discovered that integrons are surprisingly abundant in the environment and are associated with a hitherto unsuspected diversity of novel genes. In this study we will assess the diversity of environmental integrons and examine their contribution to bacterial evolution. Further, we aim to use integron systems to prospect for novel genes and contract new enzyme pathways by directed evolution.

Funded Activity Details

Start Date: 01-01-2002

End Date: 28-09-2005

Funding Scheme: Discovery Projects

Funding Amount: $231,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Molecular Evolution | Microbial Ecology | Genetic Engineering And Enzyme Technology | Genetics

ANZSRC Socio-Economic Objective (SEO)

Living resources (flora and fauna) | Biological sciences |

Other Keywords

Biological sciences | Genetic Engineering And Enzyme Technology | Genetics | Living resources (flora and fauna) | Microbial Ecology | Molecular Evolution

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