Discovery Projects - Grant ID: DP0210675

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0210675

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Genetics and evolution of Shigella O antigens. We use genome scale sequencing techniques to sequence 26 O-antigen gene clusters from Shigella. With the seven already known, this will give sequences for every O-antigen of Shigella. This will be the first time that such set is fully sequenced. Shigella are human specific pathogens, have emerged with the evolution of humans. O-antigens are important for their life and pathogenicity. This project will greatly extend our knowledge of the genetic basis and evolution of this important polymorphism. O-antigens are used for typing Shigella and also elicit strong immunity. The molecular data will help establish DNA based typing and vaccine development.

Funded Activity Details

Start Date: 05-01-2002

End Date: 30-04-2005

Funding Scheme: Discovery Projects

Funding Amount: $176,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbial Genetics | Molecular Evolution | Microbiology Not Elsewhere Classified | Microbiology

ANZSRC Socio-Economic Objective (SEO)

Infectious diseases | Diagnostics | Biological sciences |

Other Keywords

Biological sciences | Diagnostics | Infectious diseases | Microbial Genetics | Microbiology | Microbiology Not Elsewhere Classified | Molecular Evolution

Related Links