Discovery Projects - Grant ID: DP0210314

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0210314

Funding Status
Closed

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Funded Activity Summary

Meiotic recombination in Neurospora crassa: a model for the process in humans and other multicellular eukaryotes. Genes are shuffled by recombination during meiosis in the sexual cycle of higher organisms. This is best understood in yeast. Our findings show Neurospora recombination differs from yeast recombination. It is more tolerant of sequence mismatch, differs in the relative frequencies of gene conversion and crossing over, has frequently interrupted conversion tracts and has transacting genes controlling recombination hotspot activity. We propose to genetically dissect Neurospora recombination which appears to be a closer model for recombination in humans and other higher eukaryotes, where understanding recombination can assist control of genetic disease, efficient breeding in agriculture and our understanding of evolution.

Funded Activity Details

Start Date: 01-01-2002

End Date: 31-12-2005

Funding Scheme: Discovery Projects

Funding Amount: $176,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Meiosis And Recombination | Genetics

ANZSRC Socio-Economic Objective (SEO)

Biological sciences |

Other Keywords

Biological sciences | Genetics | Meiosis And Recombination

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