Discovery Projects - Grant ID: DP0209105

Funding Activity

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Funded Activity Summary

Protein degradation in mammals. One mechanism by which the regulation of protein turnover occurs is the balance between the activity of enzymes responsible for the ubiquitination and deubiquitination of target proteins. The majority of targets of this second family of enzymes are unknown. This project proposes a method for the identification of the targets of two specific mammalian deubiquitinating enzymes in order to understand their function and to begin to explore this new research field. Knowledge about this new aspect of protein degradation could provide a powerful tool to test the effect of the stabilisation or removal of specific proteins in the cell and also to develop new technologies in protein production.

Funded Activity Details

Start Date: 01-01-2002

End Date: 31-12-2002

Funding Scheme: Discovery Projects

Funding Amount: $25,000.00

Funder: Australian Research Council