Discovery Projects - Grant ID: DP0208783

Funding Activity

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Funded Activity Summary

Tail-anchored membrane proteins: prediction, targeting, assembly and function. Using computer-based searches of genome sequence data, we now have a complete list of tail-anchored membrane proteins in the yeast Saccharomyces cerevisiae. These include a number of essential proteins, such as SNAREs and TOM proteins responsible for building cellular membranes in all organisms, including man. Of the additional protein sequences discovered in the search, 8 represent proteins of known function while 19 are novel. We propose to study the subcellular location of these 19 novel proteins, and solve how they are targeted to and inserted in membranes. We will also investigate the function of the newly-discovered proteins.

Funded Activity Details

Start Date: 01-01-2002

End Date: 31-12-2006

Funding Scheme: Discovery Projects

Funding Amount: $318,000.00

Funder: Australian Research Council