Discovery Projects - Grant ID: DP0208614

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0208614

Funding Status
Closed

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Funded Activity Summary

Theoretical Studies on the KcsA Potassium Channel and the L-type Calcium Channel. All electrical activities in the brain are regulated by opening and closing of ion channels. Thus, understanding their mechanisms is a fundamental problem in biology. The project is aimed at developing a theoretical model of two important types of ion channels. Using a supercomputer, we will first deduce the shape of the microstructure formed by a protein wall. Then, using a computer simulation technique, we will construct a set of physical models of biological ion channels, which will correctly replicate experimental observations. Such a theory will link the structure and function of an ion channel through the fundamental principles of physics.

Funded Activity Details

Start Date: 01-01-2002

End Date: 31-12-2004

Funding Scheme: Discovery Projects

Funding Amount: $231,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Theoretical And Computational Chemistry Not Elsewhere Classified | Biochemistry and Cell Biology | Membrane Biology | Biophysics

ANZSRC Socio-Economic Objective (SEO)

Nervous system and disorders | Biological sciences | Mathematical sciences |

Other Keywords

Biochemistry and Cell Biology | Biological sciences | Biophysics | Mathematical sciences | Membrane Biology | Nervous system and disorders | Theoretical And Computational Chemistry Not Elsewhere Classified

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