Discovery Projects - Grant ID: DP0208537

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0208537

Funding Status
Closed

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Funded Activity Summary

Identification and characterisation of caspase inhibitors. Organisms use a tightly controlled process of cell death (termed apoptosis) to remove dangerous and unwanted cells. Dysregulation of this process can contribute to diseases such as cancer and autoimmune disease. Caspases are protease effectors of apoptosis. Regulation of their activity is vital for effective control of cell survival and death. Using a functional screening system invented by the 1st CI, we aim to isolate and characterise novel inhibitors of caspases. Such inhibitors may in time be used as targets for development of therapeutic or diagnostic reagents aimed at manipulating the apoptotic process to diagnose, prevent or treat disease.

Funded Activity Details

Start Date: 01-01-2005

End Date: 31-12-2005

Funding Scheme: Discovery Projects

Funding Amount: $156,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurogenetics | Biochemistry and Cell Biology | Cell Development (Incl. Cell Division And Apoptosis) | Genetic Development (Incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

Infectious diseases | Nervous system and disorders | Organs, diseases and abnormal conditions not elsewhere classified |

Other Keywords

Biochemistry and Cell Biology | Cell Development (Incl. Cell Division And Apoptosis) | Genetic Development (Incl. Sex Determination) | Infectious diseases | Nervous system and disorders | Neurogenetics | Organs, diseases and abnormal conditions not elsewhere classified

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