Discovery Projects - Grant ID: DP0208190

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0208190

Funding Status
Closed

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Funded Activity Summary

Cross-linked Tyrosine Residues in Peptides and Proteins. Many peptides and proteins have recently been found to contain unusual structural modifications, commonly in the form of cross-linked tyrosine residues. The aims of this project are to design and synthesise examples of these cross-linked tyrosine structures, thereby enabling the preparation of models of the modified proteins. Outcomes of this research will include an increased understanding of the relationship between the three-dimensional structure and biological activity of peptides/proteins, the generation of lead compounds for new anti-bacterial and anti-fungal pharmaceuticals, and the preparation of biological 'markers' of the processes involved in neurodegenerative diseases and aging.

Funded Activity Details

Start Date: 01-02-2002

End Date: 31-12-2005

Funding Scheme: Discovery Projects

Funding Amount: $300,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Organic Chemistry | Biological And Medical Chemistry | Organic Chemical Synthesis |

ANZSRC Socio-Economic Objective (SEO)

Clinical health not specific to particular organs, diseases and conditions | Treatments (e.g. chemicals, antibiotics) | Chemical sciences

Other Keywords

Biological And Medical Chemistry | Chemical sciences | Clinical health not specific to particular organs, diseases and conditions | Organic Chemical Synthesis | Organic Chemistry | Treatments (e.g. chemicals, antibiotics)

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