Discovery Projects - Grant ID: DP0208178

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0208178

Funding Status
Closed

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Funded Activity Summary

The Role of High-Frequency Antigenic Variation in The Pathogenesis of Mycoplasma infection. The main goal of the proposed project is to understand the molecular mechanisms of phase/antigenic variation and its effects on mycoplasma pathogenesis. In this context I will use the well-characterised Mycoplasma synoviae haemagglutinin, MSPA, to establish the role of its phase-variable expression in the type and extent of M. synoviae disease. Additionally, the relationship between MSPA phase variation and gene rearrangements in the MSPB-encoding gene will be elucidated. The results will contribute to our understanding of the pathogenesis of bacterial disease and of the evolution of pathogenic mechanisms in bacterial pathogens.

Funded Activity Details

Start Date: 02-05-2002

End Date: 31-12-2005

Funding Scheme: Discovery Projects

Funding Amount: $217,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Veterinary Sciences | Microbiology (Excl. Virology) | Gene Expression | Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall)

ANZSRC Socio-Economic Objective (SEO)

Infectious diseases | Poultry | Diagnostic methods |

Other Keywords

Cellular Interactions (Incl. Adhesion, Matrix, Cell Wall) | Diagnostic methods | Gene Expression | Infectious diseases | Microbiology (Excl. Virology) | Poultry | Veterinary Sciences

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