Discovery Projects - Grant ID: DP0208082

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0208082

Funding Status
Closed

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Funded Activity Summary

The sulfate anion transporter gene, Sat1: physiology, regulation and developmental expression. Sulfate is an essential nutrient for cell growth and survival. The kidneys and liver help regulate sulfate levels in the body, by yet unknown mechanisms. Recently, we cloned a gene, Sat1, expressed in mouse liver and kidneys, which may be responsible for body sulfate maintenance. In this study, we will determine the physiological importance of Sat1 in cell growth/survival and in controlling body sulfate levels. We will generate and characterise a Sat1 lacking mouse, study its expression during development and its effects on other genes. We will elucidate how body sulfate levels are maintained and its importance in cell growth/development.

Funded Activity Details

Start Date: 01-01-2002

End Date: 31-12-2005

Funding Scheme: Discovery Projects

Funding Amount: $141,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Physiology | Gene Expression | Physiology | Animal Physiology—Cell

ANZSRC Socio-Economic Objective (SEO)

Digestive system and disorders | Urogenital system and disorders | Organs, diseases and abnormal conditions not elsewhere classified |

Other Keywords

Animal Physiology—Cell | Cell Physiology | Digestive system and disorders | Gene Expression | Organs, diseases and abnormal conditions not elsewhere classified | Physiology | Urogenital system and disorders

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