Discovery Early Career Researcher Award - Grant ID: DE240101101

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DE240101101

Funding Status
Active

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Funded Activity Summary

Dissecting the heterogeniety of human tissue-resident memory T cells. Tissue-resident memory T cells (TRM) are key to immune protection against infection and cancer, yet dysfunctional TRM cause autoimmune disease. Whilst much of our understanding of TRM comes from animal models, how these cells work in humans is largely unknown. This project aims to define the phenotypic, functional and regulatory heterogeneity of human TRM subsets in organs like the gut, liver, and skin using a unique human organ donor tissue resource. The expected outcomes are to generate fundamental new knowledge that will have significance for the development of new therapies against infectious diseases, cancer and autoimmunity.

Funded Activity Details

Start Date: 01-01-2024

End Date: 31-12-2029

Funding Scheme: Discovery Early Career Researcher Award

Funding Amount: $452,077.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular immunology | Cell development proliferation and death | Immunology | Infectious diseases

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Cell development proliferation and death | Cellular immunology | Expanding Knowledge In the Biological Sciences | Immunology | Infectious diseases

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